Pereira, Jonalba MendesArisawa, Emilia Angela Lo SchiavoMaia Filho, Antônio Luiz MartinsSilva, José FigueredoAlves, NicolySilveira, Carolina Hahn daVieira, Lucia2026-01-132026-01-13https://repositorio.univap.br/handle/123456789/1078Background: The wound healing process presents notable challenges for nurs- ing teams, requiring extensive knowledge of wound care materials. A nanoparticle-free, bioabsorbable pol-yvinyl alcohol (PVA) with citric acid (CA) dressing produced by simple electrospin-ning was evaluated to treat acute wound healing in rats. This PVA-CA combi- nation promotes crosslinking, increases the dressing capacity of absorption and confers heal-ing properties due to the citric acid antioxidant action. Methods: The dressing was tested in a quantitative experiment on 1.9 cm acute dermatological lesions in rats (n = 12), com-paring the PVA-CA-treated group with the untreated control group (CG). Samples were collected at 3, 7 and 14 days after lesion induction to evaluate the inflammatory process and tissue healing. Results: The macroscopic and histological data on the third day showed similar characteristics in both groups; however, after fourteen days, the PVA- CA group exhibited complete healing, accompanied by recomposition of the skin layers, whereas the wounds in the CG did not close completely. Conclusions: The results highlight that electrospun PVA-AC dressings improve healing outcomes and constitute a prom-ising and affordable solution, providing a suitable environment for tissue repair, re-ducing in- flammatory cell infiltration, blood vessel formation, and restoration of epi-thelial tissue, reducing the time of the healing process of acute wounds.PDFen-USArtigos de PeriódicosEuropean Burn Journal10.3390/ebj6020018DressingsBioabsorbableWound healingPolyvinyl alcohol–citric acidPEREIRA, J. M. et al. Bioabsorbable Poly(vinyl alcohol)–Citric Acid Dressings: Wound Healing Studies in an Experimental In Vivo Model. European Burn Journal, v. 6, n. 2, p. 1-13, 2025. Disponível em: https://www.mdpi.com/2673-1991/6/2/18.Universidade do Vale do ParaíbaUniversidade do Estado do Piauí