Produção acadêmica-PPGPM
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Item Piezoelectric calcium modified barium titanate for bone regenerationMadeira, Ricardo M. D.; Vieira, Tânia; Silva, Jorge Carvalho; Oliveira, Ivone Regina de; Borges, João Paulo; Lima, Maria Margarida Rolim Augusto; Lança, Maria Carmo; Marinha Grande, PortugalSolid state reaction was used to produced barium titanate modified with calcium (BCT) showing the presence of the piezoelectric tetragonal phase after sintering at 1350 ◦C. Bioglass 45S5 (BG) was synthetized by sol-gel route. From these two materials and commercial hydroxyapatite (HAp) were obtained composites. The BG produced showed some cytotoxic character that was weakened by passivation. All other materials were non-cytotoxic. Contact polarization at constant temperature was chosen composites polarization. Electric/dielectric properties were evaluated by thermally stimulated depolarization currents (TSDC). The material showed bioactivity with the composite with BCT/BG/HAp 90/5/5 (wt%) showing increased bioactivity. In vitro test showed high proliferation rates for the composites.