Properties of strontium-containing BG 58S produced by alkali-mediated sol-gel process

Página do item simplificado
dc.contributor.authorOliveira, Ivone Regina de
dc.contributor.authorBarbosa, Ana Maria
dc.contributor.authorSantos, Kennedy Wallace dos
dc.contributor.authorLança, Maria Carmo
dc.contributor.authorLima, Maria Margarida Rolim Augusto
dc.contributor.authorVieira, Tânia
dc.contributor.authorSilva, Jorge Carvalho
dc.contributor.authorBorges, João Paulo
dc.date.accessioned2025-03-21T12:30:28Z
dc.date.available2025-03-21T12:30:28Z
dc.date.issued22022
dc.description.abstractAmong many bioglass (BG) compositions, gel-BG 58S has been indicated in the literature for applications as bone graft due to its promising use to repair bone defects. However, its physical and biological properties also depend of choice of precursors. The use of phosphoric acid as a source of P2O5 changes the thermal behavior of BG and in the presence of HNO3 increases the rate of hydrolysis and reduces the size of sol particles, thus influencing the surface area and in turn rate of apatite formation of bioactive glasses. In addition, the addition of concentrated NH4OH decreases the gelation time and new bioactive materials have been produced using Ca/Sr substitution in BG compositions. Thus, the aim of this work was to prepare BG 58S by the sol-gel technique at room temperature using phosphoric acid (PA) as the phosphorus precursor compared with conventional precursor triethylphosphate (TEP) and to evaluate the effect of the adding NH4OH (1 or 2 M) as gelation catalyst in order to select the better route to Sr incorporate. The products were characterized using XRD, FTIR and confocal Raman spectroscopy. The composition prepared with 1M NH4OH (PA-1M) presented more evidence of NBO bonds, and the absence of crystallinity. Thus, BG 58S-5 wt% Sr was prepared using the alkali-mediated sol-gel process (PA-1M) and characterized as the techniques mentioned in addition to bioactivity and cytotoxicity assays. Both compositions showed the development of a layer of apatite when treated in a simulated body fluid (SBF). Strontium composition showed higher cell viability and more evidence of calcium phosphate formation while calcium carbonate is mainly identified in strontium-free composition.
dc.description.physical10 p.
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.uriFAPESP (#2019/15960-6) CNPq (303149/2018-3)
dc.format.mimetypePDF
dc.identifier.affiliationUniversidade do Vale do Paraíba
dc.identifier.affiliationNOVA University Lisbon
dc.identifier.bibliographicCitationOLIVEIRA, Ivone Regina de et al. Properties of strontium-containing BG 58S produced by alkali-mediated sol-gel process. Ceramics International, v. 48, n. 8, p. 11456-11465, 2022. Disponível em:
dc.identifier.doi10.1016/j.ceramint.2022.01.002
dc.identifier.urihttps://repositorio.univap.br/handle/123456789/736
dc.language.isoen_US
dc.publisherElsevier
dc.rights.holderCeramics International
dc.subject.keywordGel-BG 58S
dc.subject.keywordPhosphorus precursors
dc.subject.keywordGelation catalyst
dc.subject.keywordStrontium
dc.subject.keywordBioactivity
dc.titleProperties of strontium-containing BG 58S produced by alkali-mediated sol-gel process
dc.typeArtigos de Periódicos

Arquivos

Pacote Original
Agora exibindo 1 - 2 de 2
Nenhuma Miniatura disponível
Nome:
Properties of strontium-containing BG 58S produced by alkali-mediated sol-gel process.pdf
Tamanho:
10.96 MB
Formato:
Adobe Portable Document Format
Descrição:
Acesso Via CAPES
Baixar
Imagem de Miniatura
Nome:
Properties of strontium-containing BG 58S produced by alkali-mediated sol-gel process.pdf
Tamanho:
276.62 KB
Formato:
Adobe Portable Document Format
Baixar
Licença do Pacote
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Baixar

Coleções

Produção acadêmica-PPGPM