Calcium Aluminate Cement Blends Containing Bioactive Glass and Strontium for Biomaterial Applications

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dc.contributor.authorBarbosa, Ana Margarida
dc.contributor.authorSantos, Kennedy Wallace dos
dc.contributor.authorGonçalves, Irene S.
dc.contributor.authorLeite, Priscila Maria Sarmeiro Corrêa Marciano
dc.contributor.authorMartorano, Antonio Secco
dc.contributor.authorGrisote, Gabriela
dc.contributor.authorRaucci, Larissa Moreira Spinola de Castro
dc.contributor.authorOliveira, Paulo Tambasco de
dc.contributor.authorRaniero, Leandro José
dc.contributor.authorOliveira, Ivone Regina de
dc.date.accessioned2025-04-22T14:34:15Z
dc.date.available2025-04-22T14:34:15Z
dc.date.issued22021-09-05
dc.description.abstractIn this work blends based on calcium aluminate cement (CAC) containing bioactive glass (BG) (5, 7.5 and 10 wt%) and strontium oxide (1 wt%) were produced aiming improve their bioactivity and the capacity to stimulate the bone regeneration. In the first part, the blends containing only BG were characterized as theoretical density, microhardness, uniaxial cold crush strength after SBF and apparent porosity and pore size distribution before and after SBF treatment. In the second part, bioactivity and cell culture tests were also conducted in the blends containing BG and strontium oxide. The addition of 7.5 wt% of BG in homogeneous calcium aluminate cement (CH) improved its mechanical properties as microhardness and uniaxial cold crushing strength. The blends were more bioactive due to the presence of a highly soluble amorphous phase as confirmed by means of SEM/EDX mainly for 7.5 wt% BG without and with Sr from 1 day in SBF. FTIR analyses indicated the formation the apatite-like phase by means of increase of intensity of the PO43- peaks after SBF treatment. All blends allowed the development of the osteoblastic phenotype and the formation of mineralized matrix increased due to the inclusion of BG and Sr promoting the osteogenesis process.
dc.description.physical15 p.
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipFinanciadora de Estudos e Projetos (Finep)
dc.description.uriCNPq: 303149/2018-3; FAPESP: 2019/15960-6; Finep: 01.13.0275.00 and 01.18.0053.00.
dc.format.mimetypepdf
dc.identifier.affiliationUniversidade do Vale do Paraíba
dc.identifier.affiliationUniversidade do Vale do Paraíba
dc.identifier.affiliationUniversidade do Vale do Paraíba
dc.identifier.affiliationUniversidade do Vale do Paraíba
dc.identifier.affiliationUniversidade de São Paulo
dc.identifier.affiliationUniversidade de Ribeirão Preto
dc.identifier.affiliationUniversidade de Ribeirão Preto
dc.identifier.affiliationUniversidade de São Paulo
dc.identifier.affiliationUniversidade do Vale do Paraíba
dc.identifier.affiliationUniversidade do Vale do Paraíba
dc.identifier.bibliographicCitationBARBOSA, A. M. et al. Calcium Aluminate Cement Blends Containing Bioactive Glass and Strontium for Biomaterial Applications. Materials Research, [s. l.], v. 24, n. 6, p. e20210223, 2021. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392021000600217&tlng=en.
dc.identifier.doihttps://doi.org/10.1590/1980-5373-MR-2021-0223
dc.identifier.urihttps://repositorio.univap.br/handle/123456789/872
dc.language.isoen
dc.publisherSciELO
dc.rights.holderA. M. Barbosa
dc.rights.holderK. W. dos Santos
dc.rights.holderI. S. Gonçalves
dc.rights.holderP. M. S. C. M. Leite
dc.rights.holderAntonio Secco Martorano
dc.rights.holderGabriela Grisote
dc.rights.holderLarissa Moreira Spinola de Castro Raucci
dc.rights.holderPaulo Tambasco de Oliveira
dc.rights.holderLeandro José Raniero
dc.rights.holderIvone Regina de Oliveira
dc.subject.keywordCalcium aluminate cement
dc.subject.keywordBioactive glass
dc.subject.keywordStrontium
dc.subject.keywordBioactivity
dc.subject.keywordIn vitro tests
dc.titleCalcium Aluminate Cement Blends Containing Bioactive Glass and Strontium for Biomaterial Applications
dc.typeArtigos de Periódicos

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