Adverse effects of topical photodynamic therapy in rosacea: Case report

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dc.contributor.authorSebbe-Santos, Priscilla Fróes
dc.contributor.authorMiquilini, Patrícia
dc.contributor.authorPinto, Juliana Guerra
dc.contributor.authorMenezes, Priscila Fernanda Campos de
dc.contributor.authorFerreira-Strixino, Juliana
dc.date.accessioned2025-02-07T18:54:49Z
dc.date.available2025-02-07T18:54:49Z
dc.date.issued22024-02
dc.description.abstractRosacea is a chronic and inflammatory skin condition, with relapses being a common characteristic. Its treatments are based on cosmetics, drugs, and the application of procedures based on high-powered light. Photodynamic Cosmetic Therapy (PCT) combines light, a photosensitizer (PS), and molecular oxygen present in tissues, generating photochemical reactions capable of causing tissue and vascular destruction, stimulating tissue repair. We report a case with an adverse effect caused by applying PCT, using 2 % 5-aminolevulinic acid (ALA 2 %), and irradiated with amber LED light associated with infrared radiation for the control of rosacea. A patient with subtype II rosacea underwent PCT treatment of 3 sessions at 21-day intervals, being evaluated using photographic images and Wood’s lamp. In the first session of the therapy, an exacerbated inflammatory process was observed. Such an adverse event is estimated to be as a result of the patient using ointment containing corticosteroids for a short period. With the use of medications, it was possible to recover the appearance of the skin thoroughly, and after 21 days, the treatment sessions were performed again. Despite the complication that affected the patient in this study, positive effects were found after the pharmacological therapeutic measures were adopted.
dc.description.physical3f.
dc.format.mimetypepdf
dc.identifier.affiliationUniversidade do Vale do Paraíba
dc.identifier.affiliationInstituto Priscila Menezes & Harmonização Facial
dc.identifier.affiliationUniversidade do Vale do Paraíba
dc.identifier.affiliationUniversidade de São Paulo
dc.identifier.affiliationUniversidade do Vale do Paraíba
dc.identifier.bibliographicCitationSEBBE-SANTOS, P. F. et al. Adverse effects of topical photodynamic therapy in rosacea: Case report. Photodiagnosis and Photodynamic Therapy, [S. l.], v. 45, p. 103871, fev. 2024. Disponível em: https://linkinghub.elsevier.com/retrieve/pii/S1572100023005987.
dc.identifier.doi10.1016/j.pdpdt.2023.1
dc.identifier.urihttps://repositorio.univap.br/handle/123456789/559
dc.language.isoen_US
dc.publisherElsevier
dc.rights.holderJuliana Ferreira-Strixino
dc.subject.keywordRosacea
dc.subject.keywordAdverse effects
dc.subject.keywordPhotodynamic Therapy
dc.titleAdverse effects of topical photodynamic therapy in rosacea: Case report
dc.typeArtigos de Periódicos

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